Hotels of Earth

Twentyone Hotel

★★★★ Via Cola Di Rienzo 23, Rome, IT

8.3 guest rating· 4854 reviews

About this hotel

Modern Boutique Hotel on Rome's Best Shopping Street

The Twentyone Hotel offers a sleek stay on Via Cola di Rienzo, a prime shopping destination in Rome. Just a short stroll away from iconic landmarks like Castel Sant'Angelo and the historic center, this modern boutique hotel is the perfect blend of style and convenience.

Ultra-Modern Rooms and Dining Experience

Experience luxury in every detail with ultra-modern rooms boasting minimalist decor and top-notch amenities including LCD satellite TV, air conditioning, minibar, and complimentary WiFi. Indulge in a delightful culinary journey at the on-site restaurant offering traditional Roman and classic Italian dishes paired with a wide selection of wines and champagne.

Prime Location in Elegant Prati District

Located in the upscale Prati district, the hotel is a stone's throw away from the Vatican and Saint Peter's Basilica, making it an ideal choice for travelers interested in exploring the city's rich history. With easy access to Lepanto Metro Station and bus links to Roma Termini Train Station, your Roman adventure begins at the doorstep of Twentyone Hotel.

Book your stay now and elevate your Roman holiday experience at Twentyone Hotel.

Rooms & rates

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Superior Double or Twin Room

Sleeps 2 · 25 m² · Double bed

  • Desk
  • Bathrobe
  • Private bathroom
  • Bathroom emergency pull cord
  • Free WiFi

<p><strong>1 Double Bed</strong></p><p>269 sq feet </p><br/><p><b>Internet</b> - Free WiFi and wired internet access</p><p><b>Entertainment</b> - Flat-screen TV with premium channels and pay movies</p><p><b>Food & Drink</b> - Room service (limited) and minibar (fees may apply)</p><p><b>Sleep</b> - Premium bedding and bed sheets </p><p><b>Bathroom</b> - Private bathroom, shower, bathrobes, and free toiletries</p><p><b>Practical</b> - Safe, desk, and phone</p><p><b>Comfort</b> - Climate-controlled air conditioning and daily housekeeping</p><p><b>Accessibility</b> - Bathroom emergency pull cord</p><p>Non-Smoking</p>

Twin Room

Sleeps 3 · 18 m² · 2× Twin bed

  • Desk
  • Air conditioning
  • Private bathroom
  • Emergency cord in bathroom
  • Coffee/tea maker

This air-conditioned room comes with LCD TV, mini-bar, and free WiFi.

Deluxe Double or Twin Room

Sleeps 3 · 23 m² · Double bed

  • Desk
  • Private bathroom
  • Bathroom emergency pull cord
  • Free WiFi
  • Minibar

<p><strong>1 Double Bed OR 2 Twin Beds</strong></p><p>248-sq-foot individually decorated room with a balcony </p><br/><p><b>Internet</b> - Free WiFi and wired internet access</p><p><b>Entertainment</b> - Flat-screen TV with premium channels and pay movies</p><p><b>Food & Drink</b> - Room service (limited) and minibar (fees may apply)</p><p><b>Sleep</b> - Premium bedding and bed sheets </p><p><b>Bathroom</b> - Private bathroom, shower, designer toiletries, and a hair dryer</p><p><b>Practical</b> - Safe, desk, and phone; cribs (free) available on request</p><p><b>Comfort</b> - Climate-controlled air conditioning and daily housekeeping</p><p><b>Accessibility</b> - Bathroom emergency pull cord</p><p><b>Need to Know</b> - No rollaway/extra beds available</p><p>Smoking And Non-Smoking</p>

Double Room

Sleeps 3 · 18 m² · Queen bed

  • Desk
  • Air conditioning
  • Private bathroom
  • Emergency cord in bathroom
  • Coffee/tea maker

This air-conditioned room comes with LCD TV, mini-bar, and free WiFi.

Deluxe Double Room

Sleeps 2 · 23 m² · Queen bed

  • Desk
  • Air conditioning
  • Private bathroom
  • Emergency cord in bathroom
  • Coffee/tea maker

Featuring a balcony, this larger, air-conditioned room comes with LCD TV, mini-bar, and free WiFi. Some have views of St. Peter's Basilica.

Triple Room

Sleeps 3 · 22 m² · 3× Twin bed

  • Desk
  • Air conditioning
  • Private bathroom
  • Emergency cord in bathroom
  • Coffee/tea maker

This air-conditioned room comes with LCD TV, mini-bar, and free WiFi.

Superior Double Room

Sleeps 2 · 22 m² · Extra-large double bed (Super-king size)

  • Desk
  • Air conditioning
  • Bathrobe
  • Private bathroom
  • Emergency cord in bathroom

This air-conditioned room comes with LCD TV, mini-bar, and a round bed. It also offers a private bathroom with a spa bath, free bathrobes and slippers. WiFi is free.

Family Room (4 Adults)

Sleeps 4 · 29 m² · 2× Twin bed, Queen bed

  • Desk
  • Air conditioning
  • Private bathroom
  • Emergency cord in bathroom
  • Coffee/tea maker

This large air-conditioned room comes with LCD TV, mini-bar, and free WiFi. It offers free bathrobes and slippers.

Deluxe Twin Room

Sleeps 2 · 23 m² · 2× Twin bed

  • Desk
  • Air conditioning
  • Private bathroom
  • Emergency cord in bathroom
  • Coffee/tea maker

Featuring a balcony, this large, air-conditioned room comes with LCD TV, mini-bar, and free WiFi.

Amenities

  • WiFi available
  • Fitness center
  • Parking
  • Parking garage
  • Private parking
  • Breakfast in the room
  • Restaurant
  • Bar
  • Barber/beauty shop
  • Screens / Barriers between staff and guests for safety
  • Snack bar
  • Air conditioning
  • 24-hour front desk
  • Tour desk
Show all 75 amenities
  • Room service
  • Non-smoking rooms
  • Airport shuttle
  • Airport shuttle (additional charge)
  • Airport drop off
  • Airport pick up
  • Allergy-free room
  • Cashless payment available
  • CCTV in common areas
  • Cleaning standards that are effective against Coronavirus
  • Coffee Shop on site
  • Concierge service
  • Contactless check-in/check-out
  • Daily housekeeping
  • Designated smoking area
  • Dry cleaning
  • Electric vehicle charging station
  • Emergency cord in bathroom
  • Express check-in/check-out
  • Facilities for disabled guests
  • Fax/photocopying
  • Fire extinguishers
  • First aid kit available
  • Food delivered to guest room
  • Fruits
  • Garden
  • Guest rooms disinfected between stays
  • Guests can opt-out any cleaning services during stay
  • Hand sanitizer in guest room and key areas
  • Heating
  • Invoice provided
  • Ironing service
  • Key card access
  • Kid meals
  • Kid-friendly buffet
  • Laundry
  • Laundry washed per local authority guidelines
  • Lift / Elevator
  • Luggage storage
  • Outdoor furniture
  • Packed lunches
  • Physical distancing in dining areas
  • Physical distancing rules followed
  • Process in place to check health of guests
  • Property cleaned by professional cleaning companies
  • Safety deposit box
  • Sanitized tableware & silverware
  • Security alarm
  • Shared lounge/TV area
  • Shared stationery like menus, pens are removed
  • Shuttle service
  • Shuttle service (additional charge)
  • Smoke alarms
  • Soundproof rooms
  • Special diet menus - on request
  • Staff adhere to local safety protocols
  • Terrace
  • Thermometers for guests provided by property
  • Toilet with grab rails
  • Wheelchair accessible
  • Wine/champagne

Location

© OpenStreetMap contributors

Via Cola Di Rienzo 23, Rome, IT

Check-in
from 03:00 PM to 12:00 AM
Check-out
until 11:00 AM

What guests say8.34854 reviews

+ Great location+ Helpful staff+ Clean rooms− Small rooms− Limited breakfast options− Varying room quality
Cleanliness8.1
Service8.8
Location9.1
Room Quality7.6
Amenities8.1
Value for Money8.6

Ótima experiência

10.0
Livia · BR · 2026-07-24

Guest review

3.0

It was in a nice area with plenty of restaurants near it as well as not to far from the Vatican. The staff is very friendly and breakfast was delicious

− Our room smelled like smoke, it was very hot in there and my bad sunken in the middle

alejandro · US · 2026-07-24

Polecam na weekendowe zwiedzanie Rzymu, zwłaszcza osobom nastawionym na spacery.

8.0

Lokalizacja 15-25 min spacerem do Watykanu, Castel Sant Angelo, Piazza Navona i Pantheonu. Bardzo dobre śniadania, duże, czyste pokoje i łazienki, dobrze działająca klimatyzacja.

− Do dalszych atrakcji (Koloseum) brak bezpośrednich połączeń komunikacją miejską.

Michał · PL · 2026-07-23

Good to know

Please note that parking spaces are limited and subject to availability.

A deposit may be required at the property.

›Groups

When booking more than 4 rooms, different policies and additional supplements may apply.

›Parking

Private parking is possible on site (reservation is needed) and costs EUR 35 per day.

›Internet

WiFi is available in all areas and is free of charge.

›Children and extra bed policy

Children of any age are allowed.

You haven't added any extra beds.

Any type of extra bed or child's cot/crib is upon request and needs to be confirmed by management.

›Pets

Pets are not allowed.