Hotels of Earth

Hotel Sant' Anna

★★★ via borgo pio 134, Rome, RM, 193, Rome, IT

9.4 guest rating· 136 reviews

About this hotel

Discover the charm of Hotel Sant' Anna, your perfect gateway to the heart of Rome's historic treasures.

Exceptional Location

Nestled just a 4-minute stroll from St. Peter's Square and St. Peter's Basilica, enjoy unparalleled access to the city's iconic landmarks, including the Vatican Museums and Sistine Chapel, all within walking distance.

Comfort and Convenience

Our 20 well-appointed guestrooms feature minibars, flat-screen televisions, and complimentary wireless internet access to keep you connected during your stay. Experience the luxury of modern amenities designed for your ultimate comfort.

Delightful Dining

Kickstart your day with a flavorful buffet breakfast served daily from 7:00 AM to 10:00 AM. Our concierge services are also at your disposal, ensuring all your needs are met while you explore the historic surroundings.

Experience the allure of Rome like never before—book your stay at Hotel Sant' Anna today!

Rooms & rates

Pick your dates — prices are live, not cached.

Classic Quadruple Room

Sleeps 4 · 28 m² · Queen Bed, 2× Twin bed

  • Desk
  • Private bathroom
  • Coffee/tea maker
  • Free WiFi
  • Minibar

<p><strong>1 Queen Bed and 2 Twin Beds</strong></p><p>301 sq feet </p><br/><p><b>Internet</b> - Free WiFi </p><p><b>Entertainment</b> - Flat-screen TV </p><p><b>Food & Drink</b> - Coffee/tea maker, minibar (fees may apply), and electric kettle</p><p><b>Sleep</b> - Hypo-allergenic bedding, blackout drapes/curtains, and bed sheets </p><p><b>Bathroom</b> - Private bathroom, bathtub or shower, and rainfall showerhead</p><p><b>Practical</b> - Safe, desk, and phone; cribs (free) available on request</p><p><b>Comfort</b> - Climate-controlled air conditioning and daily housekeeping</p><p><b>Accessibility</b> - Hardwood flooring in room</p><p><b>Need to Know</b> - Toothbrush and toothpaste not available</p><p>Non-Smoking</p>

Classic Triple Room

Sleeps 3 · 25 m² · Double bed, Twin bed

  • Desk
  • Private bathroom
  • Coffee/tea maker
  • Free WiFi
  • Minibar

<p><strong>1 Double Bed and 1 Twin Bed</strong></p><p>269 sq feet </p><br/><p><b>Internet</b> - Free WiFi </p><p><b>Entertainment</b> - Flat-screen TV </p><p><b>Food & Drink</b> - Coffee/tea maker, minibar (fees may apply), and electric kettle</p><p><b>Sleep</b> - Hypo-allergenic bedding, blackout drapes/curtains, and bed sheets </p><p><b>Bathroom</b> - Private bathroom, bathtub or shower, and rainfall showerhead</p><p><b>Practical</b> - Safe, desk, and phone; cribs (free) available on request</p><p><b>Comfort</b> - Climate-controlled air conditioning and daily housekeeping</p><p><b>Accessibility</b> - Hardwood flooring in room</p><p><b>Need to Know</b> - Toothbrush and toothpaste not available</p><p>Non-Smoking</p>

Basic Double Room

Sleeps 2 · 16 m² · Queen Bed

  • Desk
  • Private bathroom
  • Coffee/tea maker
  • Free WiFi
  • Minibar

<p><strong>1 Queen Bed</strong></p><p>172 sq feet </p><br/><p><b>Internet</b> - Free WiFi </p><p><b>Entertainment</b> - Flat-screen TV </p><p><b>Food & Drink</b> - Coffee/tea maker, minibar (fees may apply), and electric kettle</p><p><b>Sleep</b> - Hypo-allergenic bedding, blackout drapes/curtains, and bed sheets </p><p><b>Bathroom</b> - Private bathroom, bathtub or shower, and rainfall showerhead</p><p><b>Practical</b> - Safe, desk, and phone</p><p><b>Comfort</b> - Climate-controlled air conditioning and daily housekeeping</p><p><b>Accessibility</b> - Hardwood flooring in room</p><p><b>Need to Know</b> - No cribs (infant beds) available, toothbrush and toothpaste not available</p><p>Non-Smoking</p>

Classic Double Room, 1 Bedroom

Sleeps 2 · 18 m² · Queen Bed

  • Desk
  • Private bathroom
  • Coffee/tea maker
  • Free WiFi
  • Minibar

<p><strong>1 Queen Bed</strong></p><p>194 sq feet </p><br/><p><b>Layout</b> - Bedroom </p><p><b>Internet</b> - Free WiFi </p><p><b>Entertainment</b> - Flat-screen TV </p><p><b>Food & Drink</b> - Coffee/tea maker, minibar (fees may apply), and electric kettle</p><p><b>Sleep</b> - Hypo-allergenic bedding, blackout drapes/curtains, and bed sheets </p><p><b>Bathroom</b> - Private bathroom, bathtub or shower, and rainfall showerhead</p><p><b>Practical</b> - Safe, desk, and phone</p><p><b>Comfort</b> - Climate-controlled air conditioning and daily housekeeping</p><p><b>Accessibility</b> - Hardwood flooring in room</p><p><b>Need to Know</b> - No cribs (infant beds) available, toothbrush and toothpaste not available</p><p>Non-Smoking</p>

Double Room Single Use

Sleeps 1 · 18 m² · Queen Bed

  • Desk
  • Private bathroom
  • Coffee/tea maker
  • Free WiFi
  • Minibar

<p><strong>1 Queen Bed</strong></p><p>194 sq feet </p><br/><p><b>Internet</b> - Free WiFi </p><p><b>Entertainment</b> - Flat-screen TV </p><p><b>Food & Drink</b> - Coffee/tea maker, minibar (fees may apply), and electric kettle</p><p><b>Sleep</b> - Hypo-allergenic bedding, blackout drapes/curtains, and bed sheets </p><p><b>Bathroom</b> - Private bathroom, bathtub or shower, and rainfall showerhead</p><p><b>Practical</b> - Safe, desk, and phone</p><p><b>Comfort</b> - Climate-controlled air conditioning and daily housekeeping</p><p><b>Accessibility</b> - Hardwood flooring in room</p><p><b>Need to Know</b> - No cribs (infant beds) available, toothbrush and toothpaste not available</p><p>Non-Smoking</p>

Classic Double Room, 1 Bedroom

Sleeps 2 · 18 m² · 2× Twin bed

  • Desk
  • Private bathroom
  • Coffee/tea maker
  • Free WiFi
  • Minibar

<p><strong>2 Twin Beds</strong></p><p>194 sq feet </p><br/><p><b>Layout</b> - Bedroom </p><p><b>Internet</b> - Free WiFi </p><p><b>Entertainment</b> - Flat-screen TV </p><p><b>Food & Drink</b> - Coffee/tea maker, minibar (fees may apply), and electric kettle</p><p><b>Sleep</b> - Hypo-allergenic bedding, blackout drapes/curtains, and bed sheets </p><p><b>Bathroom</b> - Private bathroom, bathtub or shower, and rainfall showerhead</p><p><b>Practical</b> - Safe, desk, and phone</p><p><b>Comfort</b> - Climate-controlled air conditioning and daily housekeeping</p><p><b>Accessibility</b> - Hardwood flooring in room</p><p><b>Need to Know</b> - No cribs (infant beds) available, toothbrush and toothpaste not available</p><p>Non-Smoking</p>

Amenities

  • Free WiFi
  • Breakfast available (surcharge)
  • 24-hour front desk
  • Concierge service
  • Garden
  • Luggage storage
  • Smoke-free property
  • Wheelchair accessible

Location

© OpenStreetMap contributors

via borgo pio 134, Rome, RM, 193, Rome, IT

Check-in
from 01:00 PM to 12:00 AM
Check-out
until 10:30 AM

What guests say9.4136 reviews

+ Great location+ Friendly staff+ Comfortable stay+ Clean facilities− Annoyance from street hawkers
Cleanliness9.3
Service9.8
Location9.7
Room Quality9.2
Amenities9.3
Value for Money9.3

Guest review

10.0

Hotel Sant ‘Anna is in a great location close to Vatican City, the metro, and many restaurants & tourist shops. We were comfortable and had space for our family of four. The hotel is nice, clean, quiet, and comfortable. The staff was friendly and helpful. The only downside was the annoyance of having to walk past the restaurants hawkers (with their high-pressure sales pitch to lure in you and others) who on the street in front of the hotel, but that was the trade-off for convenience.

Patricia and Charles · 2025-09-27

Guest review

10.0

Very friendly staff. Free breakfast with the stay.

Cherry · 2025-09-25

Guest review

10.0

Wonderful location, very helpful service and staff!

Stephen · 2025-09-22

Super Clean, Great Location, Pleasant Staff

10.0

The cleanest hotel I have ever stayed in. Just spotless. The location is great, especially if you want to go to the Vatican but also for the restaurants and bars every where. Staff is there 24/7 and very pleasant and helpful.

reelrush530 · MALLORYTOWN, ONTARIO · 2025-09-16

Guest review

10.0

Extremely nice and helpful staff. Room was very quaint and great access to a lot of tourist spots within a mile. Room was cleaned every day. Highly recommend

Barry A · 2025-09-11

Guest review

10.0

All of the staffs were amazing. We stayed for 5 nights and no complaints at all. Breakfast was great. This is the hotel

John · 2025-08-23

Good to know

All guests, including children, must be present at check-in and show their government-issued photo ID card or passport.

Cash transactions at this property cannot exceed EUR 5000, due to national regulations. For further details, please contact the property using information in the booking confirmation.

Only registered guests are allowed in the guestrooms.

›Pets

Pets not allowed

›Children and extra beds

No rollaway/extra beds available

›Guest type

Essential workers only - NO

›Accessibility

No elevators

›General

Professional property host/manager